Predicting Recurrent Mr Following Mv Repair for Severe Ischemic Mr: Insights from the Ctsn Severe Imr Trial

The Cardiothoracic Surgical Trials Network recently reported that a third of patients after mitral valve repair for ischemic MR developed at least moderate recurrent MR at 1 year following surgery.  This begs the question as to which patients with ischemic MR would benefit from repair vs. replacement.  The present publication explored the development of a model to discriminate those patients that were more likely to develop recurrent MR following repair.  The model included the following preoperative variables:  age, BMI, sex, race, EROA, basal aneurysm/dyskinesis, NYHA, history of CABG, PCI, or ventricular arrhythmias.  The model demonstrated good discrimination with an area under the ROC curve of 0.82.