Allografts in aortic position: Insights from a 27-year, single-center prospective study

A single institution experience is reported for outcomes of aortic allograft use in 353 pts undergoing 92 subcoronary and 261 root replacements.  Hospital mortality was 5.9%.  Mean follow-up was 12 years, during which time 113 pts died.  20-year survival was 41%.  117 pts required valve-related reoperations.  Long-term mortality was related to LV dilatation and severe AR.