Association Between Preoperative Aspirin-dosing Strategy and Mortality After Coronary Artery Bypass Graft Surgery

The timing and dosage of preoperative ASA administration was evaluated with regard to CABG outcomes in a series of 3018 pts.  Dosing within 24 hrs of surgery was associated with a 50% lower mortality rate and an 81mg dose was associated with a 50% or greater reduction in mortality compared to a 325mg dose or no ASA.