Changes of Esophagogastric Junctional Adenocarcinoma and Gastroesophageal Reflux Disease Among Surgical Patients During 1988–2012: A Single-institution, High-volume Experience in China

This longitudinal review of single institution experience with GEJ adenocarcinomas identified time-related trends.  The proportion of GEJ tumors compared to all esophageal cancers increased from 22% to 36%.  GERD increased from 7% to 11%.  An increased in GERD was associated with an increased in the prevalance of Seiwert I tumors.  There was  a significant increase in the use of total gastrectomy to treat these cancers (20% vs 42%).