Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes – the FACTOR-64 Randomized Clinical Trial

This trial randomized 900 pts with type 1 or 2 diabetes to screening with coronary computed tomography angiography (CCTA) or standard care and evaluated death and non-fatal coronary outcomes.  The major outcome was a composite of death, MI, and admission for management of unstable angina.  The secondary outcome was a composite of CAD-associated death, MI, or unstable angina.  CCTA screening did not influence the rate of major or secondary outcomes.