Impact of Preoperative Chronic Kidney Disease in 2,531 High-Risk and Inoperable Patients Undergoing Transcatheter Aortic Valve Replacement in the PARTNER Trial

This analysis of PARTNER data evaluated the impact of chronic kidney disease (CKD) on outcomes after TAVR.  Patients were grouped according to GFR as none/mild, moderate, and severe renal disease.  Severe disease was most common among women with diabetes.  Severe disease was associated with a 50% increase in 30-day mortality and 1-year cominbed mortality and all-cause rehospitalization.  Assessment of renal function may help risk stratify patients who are candidates for TAVR.