Intrapyloric Botulinum Injection Increases Postoperative Esophagectomy Complications

This retrospective review included 322 pts undergoing open esophagectomy 2005-2010.  Gastric empyting procedures included Botox (78), pyloroplasty (199), and pyloromyotomy (45).  Botox was associated with more postop reflux symptoms and required more prokinetic agents. Botox pts experienced no difference in gastric emptying, and the incidence of dumping was not reduced.