Lung volume reduction coil treatment for patients with severe emphysema: a European multicentre trial

LVR using endobronchial therapies remains experimental.  This multicenter study tested LVR coils in 60 pts for safety and efficacy.  There were a total of 18 serious adverse events.  At 6 and 12 mos, dyspnea scores decreased 11%, 6 min walk increased 30-50 m, and FEV1 increased 0.11 L.  Pts with either heterogeneous or homogeneous emphysema appeared to improve.