Mechanically Expanded Versus Self-Expanding Transcatheter Aortic Valve Replacement

The authors compared mechanically expanded TAVR to self-expanding TAVR in a randomized non-inferiority trial.  Major adverse events occurred in 20% and 17% of patients, respectively (safety measure).  The one-year rates of mortality, stroke, or paravalvular leak for the valves were 15.4% and 25.5%, respectively (effectiveness measure).  Mechanically expanded valves are not inferior to self-expanding valves and broaden the options available for high risk patients.