Methods
- Randomized and observational comparative publications were identified using Medline and Google Scholar databases (January 2003 until December 2013).
- Studies without outcome data, without DES use, or utilizing conventional bypass surgery, were excluded.
- Outcomes of interest were cardiac death, myocardial infarction (MMI), target vessel revascularization (TVR) and peri-procedural stroke.
- Data were compared using the Mantel Haenszel methods, and presented as odds ratio (OR) with 95% confidence interval, and number needed to treat (NNT).
Results
- From 230 publications, the authors identified 4 studies (2 randomized and 2 observational) that included a total of 941 patients (478 underwent MINI-CAB, and 463 received DES).
- The incidence of TVR at maximum follow-up (6-60 months) was significantly lower in the MINI-CAB group (OR:0.16 [0.08-0.30], p<0.0001, NNT=13).
- Cardiac mortality and MI were similar between MINICAB and DES at follow-up (OR:1.05 [0.44-2.47] and OR:0.83 [0.43-1.58], respectively). In addition, similar peri-procedural death (OR: 0.85 [0.21-3.47], p=0.82), MI (OR: 0.98 [0.38-2.58], p=0.97) and stroke (OR: 1.36 [0.28-6.70], p=0.70) were observed between the two treatment modalities.