Nadir Hematocrit on Bypass and Rates of Acute Kidney Injury: Does Sex Matter?

Data from a large multicenter registry were evaluated to determine whether there is a sex difference in susceptibility to acute kidney injury after CBP related to nadir hematocrit levels.  Based on a 21% hematocrit threshold, 9.5% of men and 31.9% of women were affected.  Rates of AKI were similar between the sexes.  There was a strong interaction betwen sex and nadir Hct level; men were significantly more susceptible to AKI related to nadir Hct.