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Outcomes of Unresected Ground-Glass Nodules with Cytology Suspicious for Adenocarcinoma

67 patients without a previous history of lung cancer underwent FNA of a GGO with results suspicious for, but not diagnostic of, adenocarcinoma.  47 pts who elected to undergo resection were compared to 16 who opted for observation.  6/16 observed pts developed interval growth or increase in the solid component of the GGO and 5 underwent resection or radiation therapy.  The observed group experienced no cancer-related death or distant recurrence of cancer.  The resected group experienced metastatic spread (2), development of new cancers (5), and size progression in other GGOs.

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