The prevalence and outcomes of frailty in older cancer patients: a systematic review

Data from 20 observational studies including nearly 3000 pts were reviewed to assess the prevalence of pre-frailty/frailty and clinical outcomes in older cancer patients.  Frailty was identified in 42% and pre-frailty in 43% of patients.  Combined frailty was associated with increased all cause mortality (5-yr HR 1.57), postoperative mortality, and postoperative complications.