Pulmonary homograft dysfunction after the Ross procedure using decellularized homografts—a multicenter study

This study from the Canadian Ross Registry evaluated 466 consecutive patients who underwent a Ross procedure using a decellularized cryopreserved pulmonary homograft and evaluated for pulmonary homograft dysfunction. They demonstrate that the cumulative incidence of pulmonary homograft dysfunction was 11% at 6 years with pulmonary homograft stenosis (93%)  being the most frequent cause, with an incidence of homograft reintervention of 3% at 6 years.