Randomized Phase II Study of the Anti-inflammatory Effect of Ghrelin During the Postoperative Period of Esophagectomy

This small randomized trial evaluated the potential benefits of ghrelin, an anti-inflammatory agent, in reducing the SIRS response after esophagectomy.  The ghrelin group had a reduced SIRS duration, lower CRP levels, and lower IL-6 levels compared to controls.  Pulmonary complications were reduced in the ghrelin group, but other complication incidences were similar.