Topical Vancomycin and Risk of Sternal Wound Infections: A Double-Blind Randomized Controlled Trial

A study was performed to assess the efficacy of topical vancomycin in the reduction of sternal wound infection (SWI), as this topic has become a point of contention. There was no difference between the vancomycin and saline control group at three months postoperatively, and similar findings were observed at one year. The study concluded that applying vancomycin makes no significant difference in SWI.